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How to remove the influence of different cell numbers #54

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xinghua1001 opened this issue Mar 22, 2024 · 0 comments
Open

How to remove the influence of different cell numbers #54

xinghua1001 opened this issue Mar 22, 2024 · 0 comments

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@xinghua1001
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Hi,

Thank you for developing this smart tool. After using SComatic in my data, I found that there is a strong correlation between the mutation number and the cell number we used. So here is the question: when we compare mutations between groups with different cell numbers, how can we remove the effect of cell numbers. Is there any suggestion for this concern?

Best

XL

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