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EG.5.1.1 with S:T470N, with further S:D796H (32 seqs, 10 countries), and a sub-branch with S:N450K (5 seqs, Canada) #2367

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NkRMnZr opened this issue Nov 8, 2023 · 1 comment

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@NkRMnZr
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NkRMnZr commented Nov 8, 2023

Taken from Branch 2 of Multitask sars-cov-2-variants/lineage-proposals#1014 , Mostly with one of the B.1.1.529 definition changing S:D796H (D>Y>H) / G23948C (G>T>C)

Defining Mutations: EG.5.1.1 > C21306T > C22971A(S:T470N)
Query: C6541T, G13627A, C21306T, C22971A
Earliest seq: 2023-08-08 (EPI_ISL_18213963, South Korea)
Latest seq: 2023-10-29 (EPI_ISL_18470605, Ontario, Canada)
Sampled Countries: Australia (7: QLD/6; SA/1), Canada (7: ON), USA (6: MN/2; CA; TX; UT; WA), Italy (4), UK (2: EN), Spain (2), China (1, MO), France (1), South Korea (1), Sweden (1)

Genomes:

EPI_ISL_18138048, EPI_ISL_18213963, EPI_ISL_18277441, EPI_ISL_18296533, EPI_ISL_18322922, EPI_ISL_18335701, EPI_ISL_18392772, EPI_ISL_18395635, EPI_ISL_18400833, EPI_ISL_18410941, EPI_ISL_18410950-18410951, EPI_ISL_18411001, EPI_ISL_18412979, EPI_ISL_18423795, EPI_ISL_18427023, EPI_ISL_18427296, EPI_ISL_18430448, EPI_ISL_18435019, EPI_ISL_18435032, EPI_ISL_18448040, EPI_ISL_18450374, EPI_ISL_18451074, EPI_ISL_18451085, EPI_ISL_18451090, EPI_ISL_18451107, EPI_ISL_18453604, EPI_ISL_18453665, EPI_ISL_18468308, EPI_ISL_18468315, EPI_ISL_18470605, EPI_ISL_18471631

UShER:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_2415c_b7b6c0.json?f_userOrOld=uploaded%20sample
image

Trivia:

  • A sub-branch with S:N450K/T22912G emerged, phylogenetic order follows: Main proposal > C20016T, T23948C(S:D796H) > G4207T > G4076A(ORF1a:V1271I) > T22912G/S:N450K , query for it: G4076A, G4207T, T22912G. S:N450K is less popolar than S:N450D/A22910G, only sampled about 2.1k times during the whole pandemic, recent designated lineage with it being GY.4 (XBB.1.16.2.4)
@corneliusroemer
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Designated as HK.21

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