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CRISPR Annotation Project

DOI

CRISPResso2 Annotation

Download all files 0_Functions.R 1_AnnotateCRISPResso.R, 2_runannovar.sh, and 3_Annotation_render.Rmd and the script to run it all CRISPR_Annotate.sh

CRISPR_Annotate.sh

Script to run the full pipeline. Change the .sh to executable before running

usage: CRISPR_Annotate.sh [-h] 

arguments:
  --help                show this help message and exit
  --input/-i INPUTPATH             [input_params] Path to directory containing all Alleles_Frequency_Table.zip files
  --gene/-g Gene             [input_params] Gene of Interest to grab coordinates (works only with 1 at a time)
  --start/-s Start            [input_params] Start site
  --end/-e Start              [input_params] End site
  --PAM/-p Pam                [input_params] PAM site
  --allele/-e Pam Allale      [input_params] PAM allele
  --output/-o Output          [input_params] Output


Example

chmod +x CRISPR_Annotate.sh
./CRISPR_Annotate.sh -p /scratch/nousome/ccbr1046/Annotate_B1B2repeat/ -g BRCA2