fraser-lab / MET_kinase_Inhibitor_DMS Public

Notifications You must be signed in to change notification settings
Fork 0
Star 1

Source code for the MET kinase domain inhibitor DMS

1 star 0 forks Branches Tags Activity

Notifications

Name		Name	Last commit message	Last commit date
Latest commit History 43 Commits
Data		Data
Machine_Learning		Machine_Learning
EX_rosace_effect_all.tsv		EX_rosace_effect_all.tsv
LICENSE		LICENSE
README.md		README.md
WT_rosace_effect_all.tsv		WT_rosace_effect_all.tsv
ex14_scores_filtered.tsv		ex14_scores_filtered.tsv
ex14_scores_unfiltered.tsv		ex14_scores_unfiltered.tsv
met_scores_filtered.tsv		met_scores_filtered.tsv
met_scores_unfiltered.tsv		met_scores_unfiltered.tsv

Repository files navigation

Resistance landscape of the MET kinase domain

Source code for the MET kinase domain inhibitor DMS

please cite:

Estevam, G. O., Linossi, E. M., Rao, J., Macdonald, C. B., Ravikumar, A., Chrispens, K. M., Capra, J. A., Coyote-Maestas, W., Pimentel, H., Collisson, E. A., Jura, N., & Fraser, J. S. (2024). Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning (p. 2024.07.16.603579). bioRxiv. https://doi.org/10.1101/2024.07.16.603579

Analysis code used in the manuscript found in the "Data" folder

Machine learning code and analysis can be found in the "Machine Learning" folder

About

Source code for the MET kinase domain inhibitor DMS

Custom properties

Report repository

Releases

No releases published

Packages

No packages published

Contributors 2

Languages