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Split vep_cache into vep_cache and vep_plugin_files #314

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merged 3 commits into from
Aug 15, 2024

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fellen31
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@fellen31 fellen31 commented Aug 13, 2024

This PR takes a slightly different approach than raredisease and tomte, and makes --vep_plugin_files a mandatory parameter when annotating SNVs, it also separates the VEP cache input from the VEP plugins input completely.

The reason for this is that many clusters already provide a copy of the VEP cache (without plugins), in locations without write permissions. And it feels reasonable to provide all plugin file with one vep_plugin_files instead of some with vep_cache and some with vep_plugin_files. More on this: nf-core/raredisease#594 (review)

For the tests to pass this requires updating the test data files, I will wait to do so until the other open PRs have been merged.

Closes #259.

PR checklist

  • This comment contains a description of changes (with reason).
  • If you've fixed a bug or added code that should be tested, add tests!
  • If you've added a new tool - have you followed the pipeline conventions in the contribution docs
  • Make sure your code lints (nf-core lint).
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  • Check for unexpected warnings in debug mode (nextflow run . -profile debug,test,docker --outdir <OUTDIR>).
  • Usage Documentation in docs/usage.md is updated.
  • Output Documentation in docs/output.md is updated.
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github-actions bot commented Aug 13, 2024

nf-core lint overall result: Passed ✅

Posted for pipeline commit 6d22388

+| ✅ 160 tests passed       |+
#| ❔  17 tests were ignored |#

❔ Tests ignored:

  • files_exist - File is ignored: CODE_OF_CONDUCT.md
  • files_exist - File is ignored: assets/nf-core-nallo_logo_light.png
  • files_exist - File is ignored: docs/images/nf-core-nallo_logo_light.png
  • files_exist - File is ignored: docs/images/nf-core-nallo_logo_dark.png
  • files_exist - File is ignored: .github/ISSUE_TEMPLATE/config.yml
  • files_exist - File is ignored: .github/workflows/awstest.yml
  • files_exist - File is ignored: .github/workflows/awsfulltest.yml
  • files_exist - File is ignored: conf/modules.config
  • nextflow_config - Config variable ignored: manifest.name
  • nextflow_config - Config variable ignored: manifest.homePage
  • files_unchanged - File ignored due to lint config: CODE_OF_CONDUCT.md
  • files_unchanged - File ignored due to lint config: .github/CONTRIBUTING.md
  • files_unchanged - File ignored due to lint config: .github/ISSUE_TEMPLATE/bug_report.yml
  • files_unchanged - File ignored due to lint config: assets/nf-core-nallo_logo_light.png
  • files_unchanged - File ignored due to lint config: docs/images/nf-core-nallo_logo_light.png
  • files_unchanged - File ignored due to lint config: docs/images/nf-core-nallo_logo_dark.png
  • modules_config - modules_config

✅ Tests passed:

Run details

  • nf-core/tools version 2.14.1
  • Run at 2024-08-14 15:50:21

@fellen31 fellen31 force-pushed the vep_extra_files branch 2 times, most recently from 3388c21 to fa34748 Compare August 13, 2024 17:28
@fellen31 fellen31 mentioned this pull request Aug 14, 2024
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@fellen31 fellen31 marked this pull request as ready for review August 14, 2024 11:26
@fellen31 fellen31 requested a review from a team as a code owner August 14, 2024 11:26
@fellen31 fellen31 mentioned this pull request Aug 14, 2024
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Looks good, a couple of small comments

conf/modules/snv_annotation.config Outdated Show resolved Hide resolved
docs/usage.md Outdated Show resolved Hide resolved
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@fellen31 fellen31 force-pushed the vep_extra_files branch 3 times, most recently from b4abee2 to 6d22388 Compare August 14, 2024 15:48
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Should be fixed!

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👍

@fellen31 fellen31 merged commit 341b8b5 into genomic-medicine-sweden:dev Aug 15, 2024
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@fellen31 fellen31 deleted the vep_extra_files branch August 15, 2024 13:06
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Use vep_plugins instead of putting plugins in cache
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