[NTR-cxg] atretic theca cell

[Caroline-99]

Please check that the term does not already exist by using the ontology search tool OLS:
https://www.ebi.ac.uk/ols4/ontologies/cl

Preferred term label
atretic theca cell

Synonym(s) (add reference(s), please)

Definition (free text, with reference(s), please. PubMed ID format is PMID:XXXXXX)

A theca cell undergoing atresia, marked by distinct morphological and functional changes. Morphologically, it shows rounding and an expanded cytoplasmic area in theca interna cells, along with a thickened internal theca layer and a degrading organized structure. Functionally, it exhibits reduced STAR expression in theca interna cells, lowering androgen production, and decreased ACTA2 expression in theca externa cells, weakening structural integrity. The atretic theca cell also displays altered vascularization.

PMID: 38069168
PMID: 20628033

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols4/ontologies/cl)
atretic follicular cell of ovary
'develops from' some 'theca cell'

Anatomical structure where the cell type is found (check Uberon for anatomical structures: https://www.ebi.ac.uk/ols4/ontologies/uberon)

Your ORCID

Additional notes or concerns If there are markers that uniquely identify the cell type in a particular species, they can be added here.