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NTR-pro-opiomelanocortin-neuron #2649

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merged 12 commits into from
Oct 31, 2024
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NTR-pro-opiomelanocortin-neuron #2649

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e67ad21
exact synonym
AvolaAmg Oct 15, 2024
bbbef7d
Merge branch 'master' into NTR-pro-opiomelanocortin-neuron
AvolaAmg Oct 17, 2024
2485f17
Merge branch 'master' into NTR-pro-opiomelanocortin-neuron
AvolaAmg Oct 28, 2024
155ca24
Merge branch 'master' into NTR-pro-opiomelanocortin-neuron
AvolaAmg Oct 28, 2024
24d4f31
Fix Conflict
AvolaAmg Oct 28, 2024
cb6e2bc
Merge branch 'NTR-pro-opiomelanocortin-neuron' of https://github.com/…
AvolaAmg Oct 28, 2024
79cfbf4
Merge branch 'master' into NTR-pro-opiomelanocortin-neuron
AvolaAmg Oct 28, 2024
ca22ca2
Merge branch 'master' into NTR-pro-opiomelanocortin-neuron
AvolaAmg Oct 28, 2024
c4fad09
Merge branch 'master' into NTR-pro-opiomelanocortin-neuron
AvolaAmg Oct 29, 2024
0c7eb0f
Merge branch 'master' into NTR-pro-opiomelanocortin-neuron
AvolaAmg Oct 31, 2024
5e6bf2b
Merge branch 'master' into NTR-pro-opiomelanocortin-neuron
AvolaAmg Oct 31, 2024
bfa2bbb
Merge branch 'master' into NTR-pro-opiomelanocortin-neuron
AvolaAmg Oct 31, 2024
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32 changes: 23 additions & 9 deletions src/ontology/cl-edit.owl
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Original file line number Diff line number Diff line change
Expand Up @@ -3080,6 +3080,7 @@ Declaration(Class(obo:CL_4042030))
Declaration(Class(obo:CL_4042031))
Declaration(Class(obo:CL_4042032))
Declaration(Class(obo:CL_4042033))
Declaration(Class(obo:CL_4042034))
Declaration(Class(obo:CL_4047006))
Declaration(Class(obo:CL_4047007))
Declaration(Class(obo:CL_4047011))
Expand Down Expand Up @@ -3179,6 +3180,7 @@ Declaration(Class(obo:PR_000007785))
Declaration(Class(obo:PR_000009981))
Declaration(Class(obo:PR_000010529))
Declaration(Class(obo:PR_000012318))
Declaration(Class(obo:PR_000013015))
Declaration(Class(obo:PR_000013047))
Declaration(Class(obo:PR_000013433))
Declaration(Class(obo:PR_000013502))
Expand Down Expand Up @@ -32641,17 +32643,29 @@ SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004026
SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000012318))

# Class: obo:CL_4042033 (CGRP-expressing neuron)
# Class: obo:CL_4042033 (pro-opiomelanocortin neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") obo:IAO_0000115 obo:CL_4042033 "An interneuron neuron characterized by the expression of calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide. This neuron type is involved in nociception and pain modulation by facilitating the transmission of nociceptive signals from peripheral sensory nerve endings to central nervous system structures. This neuron type is found in the dorsal root ganglia (DRG) and trigeminal ganglion, and the spinal cord dorsal horn.")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:25870542") Annotation(oboInOwl:hasDbXref "PMID:28192062") obo:IAO_0000115 obo:CL_4042033 "A neuron of the central nervous system that expresses POMC and synthesizes the POMC precursor polypeptide. This neuron type is located in the arcuate nucleus of the hypothalamus and in the nucleus tractus solitarius of the brainstem. The pro-opiomelanocortin neuron is part of the central melanocortin system and it is involved in regulating energy homeostasis, metabolism, and appetite. This neuronal type responds to hormonal signals such as levels of leptin and insulin, and its activation results in the release of α-melanocyte-stimulating hormone (α-MSH), which acts on melanocortin receptors to suppress food intake and increase energy expenditure.")
AnnotationAssertion(terms:contributor obo:CL_4042033 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042033 "2024-10-30T15:35:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasExactSynonym obo:CL_4042033 "Calcitonin gene-related peptide neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasRelatedSynonym obo:CL_4042033 "CGRP-expressing interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasRelatedSynonym obo:CL_4042033 "CGRP-positive neuron")
AnnotationAssertion(rdfs:label obo:CL_4042033 "CGRP-expressing neuron"@en)
SubClassOf(obo:CL_4042033 obo:CL_0000526)
SubClassOf(obo:CL_4042033 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))
AnnotationAssertion(terms:date obo:CL_4042033 "2024-10-15T10:17:41Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34002087") oboInOwl:hasRelatedSynonym obo:CL_4042033 "POMC neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34002087") oboInOwl:hasRelatedSynonym obo:CL_4042033 "POMC-expressing neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:28192062") Annotation(oboInOwl:hasDbXref "PMID:33633406") rdfs:comment obo:CL_4042033 "Pro-opiomelanocortin neurons have a diverse projection pattern. The neurons in the rostral arcuate nucleus project to autonomic areas, caudal arcuate POMC neurons project mainly to hypothalamic areas (Toda et al., 2017). Dysregulation of pro-opiomelanocortin neurons is associated with obesity and metabolic disorders (Quarta et al., 2020).")
AnnotationAssertion(rdfs:label obo:CL_4042033 "pro-opiomelanocortin neuron"@en)
SubClassOf(obo:CL_4042033 obo:CL_0000165)
SubClassOf(obo:CL_4042033 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000013015))

# Class: obo:CL_4042034 (CGRP-expressing neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") obo:IAO_0000115 obo:CL_4042034 "An interneuron neuron characterized by the expression of calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide. This neuron type is involved in nociception and pain modulation by facilitating the transmission of nociceptive signals from peripheral sensory nerve endings to central nervous system structures. This neuron type is found in the dorsal root ganglia (DRG) and trigeminal ganglion, and the spinal cord dorsal horn.")
AnnotationAssertion(terms:contributor obo:CL_4042034 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042034 "2024-10-30T15:35:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasExactSynonym obo:CL_4042034 "Calcitonin gene-related peptide neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasRelatedSynonym obo:CL_4042034 "CGRP-expressing interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasRelatedSynonym obo:CL_4042034 "CGRP-positive neuron")
AnnotationAssertion(rdfs:label obo:CL_4042034 "CGRP-expressing neuron"@en)
SubClassOf(obo:CL_4042034 obo:CL_0000526)
SubClassOf(obo:CL_4042034 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_4047006 (fetal artery endothelial cell)

Expand Down
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