This is a Julia implementation of sctransform, based on the paper Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression by Hafemaister and Satija.
This is an independent implementation, the original authors were not involved. Here is the original R implementation of sctransform.
The doc strings for scparams
and sctransform
describe the usage.
Also see the SingleCellProjections.jl package which provides a framework for working with Single Cell expression data and supports SCTransform.jl
.
Note that threading should be enabled in Julia for SCTransform.jl
to work optimally.