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Reference list for Introduction:

1. D. A. Dorward et al., Tissue-specific Immunopathology in Fatal COVID-19. American Journal of Respiratory and Critical Care Medicine, (2020).
2. J. A. C. Sterne et al., Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis. Jama 324, 1330-1341 (2020).
3. P. Horby et al., Dexamethasone in Hospitalized Patients with Covid-19 - Preliminary Report. N Engl J Med, (2020).
4. N. J. Brendish et al., Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital (COV-19POC): a prospective, interventional, non-randomised, controlled study. The Lancet Respiratory Medicine 8, 1192-1200 (2020).
5. K. Beard et al., Pragmatic multicentre randomised controlled trial evaluating the impact of a routine molecular point-of-care ‘test-and-treat’ strategy for influenza in adults hospitalised with acute respiratory illness (FluPOC): trial protocol. BMJ Open 9, e031674 (2019).
6. J. Legebeke et al., Distinct immune responses in patients infected with influenza or SARS-CoV-2, and in COVID-19 survivors, characterised by transcriptomic and cellular abundance differences in blood. medRxiv, 2021.2005.2012.21257086 (2021).
7. J. J. Clark et al., Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19. bioRxiv, 2020.2010.2013.334532 (2021).

More details on the work presented can be found here

Figure 1: Tissue-Specific Immunopathology in Fatal COVID-19

Full authors list for this work: David A. Dorward, Clark D. Russell, In Hwa Um, Mustafa Elshani, Stuart D. Armstrong, Rebekah Penrice-Randal, Tracey Millar, Chris E. B. Lerpiniere, Giulia Tagliavini, Catherine S. Hartley, Nadine P. Randle, Naomi N. Gachanja, Philippe M. D. Potey, Xiaofeng Dong, Alison M. Anderson, Victoria L. Campbell, Alasdair J. Duguid, Wael Al Qsous, Ralph BouHaidar, J. Kenneth Baillie, Kevin Dhaliwal, William A. Wallace, Christopher O. C. Bellamy, Sandrine Prost, Colin Smith, Julian A. Hiscox, David J. Harrison, and Christopher D. Lucas; on behalf of the ICECAP Consortium.

Figure 2: Distinct immune responses in patients infected with influenza or SARS-CoV-2, and in COVID-19 survivors, characterised by transcriptomic and cellular abundance differences in blood

Full authors list for this work: Jelmer Legebeke, Jenny Lord, Rebekah Penrice-Randal, Andres F. Vallejo, Stephen Poole, Nathan J. Brendish, Xiaofeng Dong, Catherine Hartley, John W. Holloway, Jane S. Lucas, Anthony P. Williams, Gabrielle Wheway, Fabio Strazzeri, Aaron Gardner, James P.R. Schofield, Paul J. Skipp, Julian A. Hiscox, Marta E. Polak, Tristan W. Clark, Diana Baralle

Figure 3: Manuscript in preparation

Figure 4: Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse model of COVID-19

Full authors list for this work: Jordan J. Clark*, Rebekah Penrice-Randal*, Parul Sharma, Anja Kipar, Xiaofeng Dong, Shaun H. Pennington, Amy E. Marriott, Stefano Colombo, Andrew Davidson, Maia Kavanagh Williamson, David A. Matthews, Lance Turtle, Tessa Prince, Grant L. Hughes, Edward I. Patterson, Ghada Shawli, Krishanthi Subramaniam, Jo Sharp, Lynn McLaughlin, En-Min Zhou, Joseph D. Turner, Giancarlo Biagini, Andrew Owen, Julian A. Hiscox, James P. Stewart

• Joint first author

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