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Merge pull request #1 from astrovsky01/patch-1
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Fix broken link to Watson and Crick paper
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mschatz authored Aug 27, 2024
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Expand Up @@ -43,7 +43,7 @@ We will study the leading computational and quantitative approaches for comparin

| Class | Date | Day | Topic | Assignments | Readings |
| ----- | ------ | --- | --------------------------------------------------------------- | ----------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
| 1 | 26-Aug | Mon | Introduction | [Sign Up for Piazza](https://piazza.com/jhu/fall2024/600449600649/home) | \* [Molecular Structure of Nucleic Acid (Watson and Crick, 1953, Nature)](http://www.nature.com/nature/dna50/watsoncrick.pdf) <br> \* [Biological data sciences in genome research (Schatz, 2015, Genome Research)](http://genome.cshlp.org/content/25/10/1417.full) <br> \* [Big Data: Astronomical or Genomical? (Stephens et al, 2015, PLOS Biology)](http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002195) |
| 1 | 26-Aug | Mon | Introduction | [Sign Up for Piazza](https://piazza.com/jhu/fall2024/600449600649/home) | \* [Molecular Structure of Nucleic Acid (Watson and Crick, 1953, Nature)](https://www.nature.com/articles/171737a0) <br> \* [Biological data sciences in genome research (Schatz, 2015, Genome Research)](http://genome.cshlp.org/content/25/10/1417.full) <br> \* [Big Data: Astronomical or Genomical? (Stephens et al, 2015, PLOS Biology)](http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002195) |
| 2 | 28-Aug | Wed | Genomic Technologies, kmers | Assignment 1 | \* [Coming of age: ten years of next-generation sequencing technologies (Goodwin et al, 2016, Nature Reviews Genetics)](http://www.nature.com/nrg/journal/v17/n6/full/nrg.2016.49.html) <br> \* [Guide to k-mer approaches for genomics across the tree of life (Jenike et al., 2024, arXiv)](https://arxiv.org/abs/2404.01519) |
| \* | 2-Sep | Mon | $${\color{red}\text{Labor Day}}$$ | | |
| 3 | 4-Sep | Wed | Assembly, WGA | | \* [Toward simplifying and accurately formulating fragment assembly. (Myers, 1995, J. Comp. Bio.)](http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.52.6330&rep=rep1&type=pdf) <br> \* [Velvet: Algorithms for de novo short read assembly using de Bruijn graphs (Zerbino and Birney, 2008, Genome Research)](http://genome.cshlp.org/content/18/5/821.full) <br> \* [SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing (Bankevich, et al. 2012, J Comput Biol)](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342519/) <br> \* [MUMmer: Alignment of Whole Genomes (Delcher et al, 1999, NAR)](http://mummer.sourceforge.net/MUMmer.pdf) |
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