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[NTR] CGRP-expressing neuron (#2712)
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Fixes #2445
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AvolaAmg authored Oct 31, 2024
1 parent 92e5f66 commit 2a104cf
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Showing 5 changed files with 252 additions and 94 deletions.
20 changes: 17 additions & 3 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -3079,6 +3079,7 @@ Declaration(Class(obo:CL_4042029))
Declaration(Class(obo:CL_4042030))
Declaration(Class(obo:CL_4042031))
Declaration(Class(obo:CL_4042032))
Declaration(Class(obo:CL_4042033))
Declaration(Class(obo:CL_4047006))
Declaration(Class(obo:CL_4047007))
Declaration(Class(obo:CL_4047011))
Expand Down Expand Up @@ -3347,7 +3348,7 @@ AnnotationAssertion(rdfs:label obo:IAO_0000115 "definition")

AnnotationAssertion(rdfs:label obo:IAO_0000424 "expand expression to")

# Annotation Property: obo:IAO_0000700 (preferred_root)
# Annotation Property: obo:IAO_0000700 (has ontology root term)

AnnotationAssertion(rdfs:label obo:IAO_0000700 "preferred_root")

Expand Down Expand Up @@ -3441,11 +3442,11 @@ AnnotationAssertion(rdfs:label oboInOwl:hasBroadSynonym "has_broad_synonym")

AnnotationAssertion(rdfs:label oboInOwl:hasDbXref "database_cross_reference")

# Annotation Property: oboInOwl:hasExactSynonym (has_exact_synonym)
# Annotation Property: oboInOwl:hasExactSynonym (has exact synonym)

AnnotationAssertion(rdfs:label oboInOwl:hasExactSynonym "has_exact_synonym")

# Annotation Property: oboInOwl:hasNarrowSynonym (has_narrow_synonym)
# Annotation Property: oboInOwl:hasNarrowSynonym (has narrow synonym)

AnnotationAssertion(rdfs:label oboInOwl:hasNarrowSynonym "has_narrow_synonym")

Expand Down Expand Up @@ -6845,6 +6846,7 @@ SubClassOf(obo:CL_0000378 obo:CL_0000630)
AnnotationAssertion(rdfs:label obo:CL_0000379 "sensory processing neuron")
SubClassOf(obo:CL_0000379 obo:CL_0000540)
SubClassOf(obo:CL_0000379 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))
SubClassOf(obo:CL_0000379 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0050893))

# Class: obo:CL_0000380 (thecogen cell)

Expand Down Expand Up @@ -32639,6 +32641,18 @@ SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002202 obo:UBERON_0004026
SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002215 obo:GO_0061534))
SubClassOf(obo:CL_4042032 ObjectSomeValuesFrom(obo:RO_0002292 obo:PR_000012318))

# Class: obo:CL_4042033 (CGRP-expressing neuron)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") obo:IAO_0000115 obo:CL_4042033 "An interneuron neuron characterized by the expression of calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide. This neuron type is involved in nociception and pain modulation by facilitating the transmission of nociceptive signals from peripheral sensory nerve endings to central nervous system structures. This neuron type is found in the dorsal root ganglia (DRG) and trigeminal ganglion, and the spinal cord dorsal horn.")
AnnotationAssertion(terms:contributor obo:CL_4042033 <https://orcid.org/0000-0002-0098-8958>)
AnnotationAssertion(terms:date obo:CL_4042033 "2024-10-30T15:35:08Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasExactSynonym obo:CL_4042033 "Calcitonin gene-related peptide neuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasRelatedSynonym obo:CL_4042033 "CGRP-expressing interneuron")
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34061020") oboInOwl:hasRelatedSynonym obo:CL_4042033 "CGRP-positive neuron")
AnnotationAssertion(rdfs:label obo:CL_4042033 "CGRP-expressing neuron"@en)
SubClassOf(obo:CL_4042033 obo:CL_0000526)
SubClassOf(obo:CL_4042033 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001017))

# Class: obo:CL_4047006 (fetal artery endothelial cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:34497389") obo:IAO_0000115 obo:CL_4047006 "An endothelial cell that lines an artery in the fetal circulatory system.")
Expand Down
20 changes: 10 additions & 10 deletions src/ontology/components/mappings.owl
Original file line number Diff line number Diff line change
Expand Up @@ -819,6 +819,15 @@
<owl:annotatedTarget>ZFA:0009066</owl:annotatedTarget>
<sssom:mapping_justification rdf:resource="https://w3id.org/semapv/vocab/UnspecifiedMatching"/>
</owl:Axiom>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000117">
<oboInOwl:hasDbXref>ZFA:0009067</oboInOwl:hasDbXref>
</rdf:Description>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/CL_0000117"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget>ZFA:0009067</owl:annotatedTarget>
<sssom:mapping_justification rdf:resource="https://w3id.org/semapv/vocab/UnspecifiedMatching"/>
</owl:Axiom>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000118">
<oboInOwl:hasDbXref>ZFA:0009068</oboInOwl:hasDbXref>
</rdf:Description>
Expand Down Expand Up @@ -4550,18 +4559,9 @@
<owl:annotatedTarget>FBbt:00006009</owl:annotatedTarget>
<sssom:mapping_justification rdf:resource="https://w3id.org/semapv/vocab/ManualMappingCuration"/>
</owl:Axiom>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_2000029">
<oboInOwl:hasDbXref>ZFA:0009067</oboInOwl:hasDbXref>
</rdf:Description>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/CL_2000029"/>
<owl:annotatedProperty rdf:resource="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
<owl:annotatedTarget>ZFA:0009067</owl:annotatedTarget>
<sssom:mapping_justification rdf:resource="https://w3id.org/semapv/vocab/UnspecifiedMatching"/>
</owl:Axiom>
</rdf:RDF>



<!-- Generated by the OWL API (version 4.5.26.2023-07-17T20:34:13Z) https://github.com/owlcs/owlapi -->
<!-- Generated by the OWL API (version 4.5.29) https://github.com/owlcs/owlapi -->

1 change: 1 addition & 0 deletions src/ontology/imports/go_terms.txt
Original file line number Diff line number Diff line change
Expand Up @@ -13,3 +13,4 @@ GO:0036053
GO:0036376
GO:1990573
GO:0045428
GO:0050893
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